Pentadecapeptide Arginate (PDA) is a peptide composed of a 15-chain sequence of amino acids and is a partial sequence of body protecting compounds that was discovered and isolated from human gastric (stomach) juice.

PDA works by accelerating the rate of repair of damaged blood vessels while also promoting the development of new blood vessels (angiogenesis). The creation of new blood vessel networks is a key process for wound healing.

PDA is also strongly associated with the protection of the gastrointestinal tract, especially from certain medications such as non-steroidal anti-inflammatory medications (NSAID) that can cause gastric ulcers. It has also been found to be helpful in the management of other gastrointestinal inflammatory diseases such as Ulcerative colitis and Chron’s disease.

For optimum results, PDA is most likely to be effective therapeutically if injected either by intramuscular (IM) or subcutaneous (SQ) injection. Most synthetic peptides are not absorbed well by the body if taken orally.

Potential Benefits:

• Improvement in joint health: PDA promotes healthy tendon and ligament healing by accelerating the growth and spread of fibroblasts, which are cells found in connective tissues that are involved in the creation of collagen. 

• Mends muscles and tendons: PDA has muscle and tendon mending properties, which can help repair sports related injuries where the tissues need to be rejuvenated.

• Accelerate healing: With its well-known fracture and wound healing aspects, PDA injection therapy is known to promote bone repair and improve overall bone health. 

• Protects against intestinal and gut damage: PDA can help overcome problems related to short gut (short bowel syndrome: SBS) and can help repair damaged tissues caused by inflammatory bowel disease (IBD). It can also act as an anti-ulcer agent and a NSAID (nonsteroidal anti-inflammatory drug) antidote. NSAIDs can be toxic to the gut and frequent use can lead to ulcers and an irritation of the bowels. PDA is able to counteract symptoms associated with taking aspirin, such as bleeding.